TOPAZ: A Positive-Unlabeled Convolutional Neural Network CryoEM Particle Picker that can Pick Any Size and Shape Particle
نویسندگان
چکیده
منابع مشابه
Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs
Cryo-electron microscopy (cryoEM) is fast becoming the preferred method for protein structure determination. Particle picking is a significant bottleneck in the solving of protein structures from single particle cryoEM. Hand labeling sufficient numbers of particles can take months of effort and current computationally based approaches are often ineffective. Here, we frame particle picking as a ...
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ژورنال
عنوان ژورنال: Microscopy and Microanalysis
سال: 2019
ISSN: 1431-9276,1435-8115
DOI: 10.1017/s143192761900566x